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1

Folding and misfolding of the prion protein in the secretory pathway

Tatzelt, Jörg, Winklhofer, Konstanze F

Journal:

Year:

2004

Language:

english

File:

PDF, 281 KB

english, 2004

2

[Topics in Current Chemistry] Prion Proteins Volume 305 || Prion Protein and Its Conformational Conversion: A Structural Perspective

Year:

2012

Language:

english

File:

PDF, 713 KB

english, 2012

3

Synthesis of a GPI anchor module suitable for protein post-translational modification

Miria C. Schumacher, Ulrike Resenberger, Ralf P. Seidel, Christian F. W. Becker, Konstanze F. Winklhofer, Dieter Oesterhelt, Jörg Tatzelt, Martin Engelhard

Journal:

Year:

2010

Language:

english

File:

PDF, 805 KB

english, 2010

4

Advanced Volumetric Capture and Processing

Schreer, Oliver, Feldmann, Ingo, Ebner, Thomas, Renault, Sylvain, Weissig, Christian, Tatzelt, Danny, Kauff, Peter

Journal:

SMPTE Motion Imaging Journal

Year:

2019

Language:

english

File:

PDF, 1.28 MB

english, 2019

5

Structural Instability of the Prion Protein upon M205S/R Mutations Revealed by Molecular Dynamics Simulations

Hirschberger, Thomas, Stork, Martina, Schropp, Bernhard, Winklhofer, Konstanze F., Tatzelt, Jörg, Tavan, Paul

Journal:

Biophysical Journal

Year:

2006

Language:

english

File:

PDF, 623 KB

english, 2006

6

Secretory pathway retention of mutant prion protein induces p38-MAPK activation and lethal disease in mice

Puig, Berta, Altmeppen, Hermann C., Ulbrich, Sarah, Linsenmeier, Luise, Krasemann, Susanne, Chakroun, Karima, Acevedo-Morantes, Claudia Y., Wille, Holger, Tatzelt, Jörg, Glatzel, Markus

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 2.99 MB

english, 2016

7

Insight of the Cytotoxicity of the Aggregates of Peptides or Aberrant Proteins: A Meta-Analysis

Zhou, Rong, Xu, Bing, Tatzelt, Jörg

Journal:

Year:

2014

Language:

english

File:

PDF, 746 KB

english, 2014

8

Fractionated Nuclear Extracts from Hamster Cells Catalyze Cell-Free Recombination at Selective Sequences Between Adenovirus DNA and a Hamster Preinsertion Site

Jorg Tatzelt, Katja Fechteler, Peter Langenbach and Walter Doerfler

Journal:

Proceedings of the National Academy of Sciences

Year:

1993

Language:

english

File:

PDF, 1.41 MB

english, 1993

9

The polysaccharide scaffold of PrP 27-30 is a common compound of natural prions and consists of α-linked polyglucose

Dumpitak, Christian, Beekes, Michael, Weinmann, Nicole, Metzger, Sabine, Winklhofer, Konstanze F., Tatzelt, Jörg, Riesner, Detlev

Journal:

Biological Chemistry

Year:

2005

Language:

english

File:

PDF, 162 KB

english, 2005

10

The N-terminus of Sec61p plays key roles in ER protein import and ERAD

Elia, Francesco, Yadhanapudi, Lalitha, Tretter, Thomas, Römisch, Karin, Tatzelt, Jörg

Journal:

Year:

2019

Language:

english

File:

PDF, 1.53 MB

english, 2019

11

[Topics in Current Chemistry] Prion Proteins Volume 305 || Fungal Prions: Structure, Function and Propagation

Year:

2011

Language:

english

File:

PDF, 748 KB

english, 2011

12

Scrapie prions selectively modify the stress response in neuroblastoma cells.

Tatzelt, J., Zuo, J., Voellmy, R., Scott, M., Hartl, U., Prusiner, S. B., Welch, W. J.

Journal:

Proceedings of the National Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 1.76 MB

english, 1995

13

[Topics in Current Chemistry] Prion Proteins Volume 305 || Prion Seeded Conversion and Amplification Assays

Year:

2012

File:

PDF, 292 KB

2012

14

The prion protein in neuroimmune crosstalk

Salvesen, Øyvind, Tatzelt, Jörg, Tranulis, Michael A.

Journal:

Neurochemistry International

Year:

2018

Language:

english

File:

PDF, 2.41 MB

english, 2018

15

[Topics in Current Chemistry] Prion Proteins Volume 305 || Transgenic Mouse Models and Prion Strains

Year:

2012

Language:

english

File:

PDF, 188 KB

english, 2012

16

Prion Protein Accumulation in Lipid Rafts of Mouse Aging Brain

Agostini, Federica, Dotti, Carlos G., Pérez-Cañamás, Azucena, Ledesma, Maria Dolores, Benetti, Federico, Legname, Giuseppe, Tatzelt, Jörg

Journal:

Year:

2013

Language:

english

File:

PDF, 3.09 MB

english, 2013

17

Translation of the Prion Protein mRNA Is Robust in Astrocytes but Does Not Amplify during Reactive Astrocytosis in the Mouse Brain

Jackson, Walker S., Krost, Clemens, Borkowski, Andrew W., Kaczmarczyk, Lech, Tatzelt, Jörg

Journal:

Year:

2014

Language:

english

File:

PDF, 11.93 MB

english, 2014

18

Scrapie in mice deficient in apolipoprotein E or glial fibrillary acidic protein

Tatzelt, J., Maeda, N., Pekny, M., Yang, S.-L., Betsholtz, C., Eliasson, C., Cayetano, J., Camerino, A. P., DeArmond, S. J., Prusiner, S. B.

Journal:

Year:

1996

Language:

english

File:

PDF, 985 KB

english, 1996

19

Transgenic Overexpression of the Disordered Prion Protein N1 Fragment in Mice Does Not Protect Against Neurodegenerative Diseases Due to Impaired ER Translocation

Mohammadi, Behnam, Linsenmeier, Luise, Shafiq, Mohsin, Puig, Berta, Galliciotti, Giovanna, Giudici, Camilla, Willem, Michael, Eden, Thomas, Koch-Nolte, Friedrich, Lin, Yu-Hsuan, Tatzelt, JÃ¶rg, Glatze

Journal:

Molecular Neurobiology

Year:

2020

File:

PDF, 2.79 MB

2020

20

Scrapie Prions Selectively Modify the Stress Response in Neuroblastoma Cells

Jorg Tatzelt, Jianru Zuo, Richard Voellmy, Michael Scott, Ulrich Hartl, Stanley B. Prusiner and William J. Welch

Journal:

Proceedings of the National Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 1.41 MB

english, 1995

21

The RAB GTPase RAB18 modulates macroautophagy and proteostasis

Feldmann, Anne, Bekbulat, Fazilet, Huesmann, Heike, Ulbrich, Sarah, Tatzelt, Jörg, Behl, Christian, Kern, Andreas

Journal:

Biochemical and Biophysical Research Communications

Year:

2017

Language:

english

File:

PDF, 2.21 MB

english, 2017

22

Parkin Is Protective against Proteotoxic Stress in a Transgenic Zebrafish Model

Fett, Mareike E., Pilsl, Anna, Paquet, Dominik, van Bebber, Frauke, Haass, Christian, Tatzelt, Jörg, Schmid, Bettina, Winklhofer, Konstanze F., Cookson, Mark R.

Journal:

Year:

2010

Language:

english

File:

PDF, 3.52 MB

english, 2010

23

Stress-protective signalling of prion protein is corrupted by scrapie prions

Rambold, Angelika S, Müller, Veronika, Ron, Uri, Ben-Tal, Nir, Winklhofer, Konstanze F, Tatzelt, Jörg

Journal:

The EMBO Journal

Year:

2008

Language:

english

File:

PDF, 1.57 MB

english, 2008

24

Abnormalities in Stress Proteins in Prion Diseases

Jörg Tatzelt, Richard Voellmy, William J. Welch

Journal:

Cellular and Molecular Neurobiology

Year:

1998

Language:

english

File:

PDF, 602 KB

english, 1998

25

Cellular Prion Protein Mediates Toxic Signaling of Amyloid Beta

Resenberger, Ulrike K., Winklhofer, Konstanze F., Tatzelt, Jörg

Journal:

Neurodegenerative Diseases

Year:

2012

Language:

english

File:

PDF, 95 KB

english, 2012

26

GPI-anchor signal sequence influences PrPC sorting, shedding and signalling, and impacts on different pathomechanistic aspects of prion disease in mice

Puig, Berta, Altmeppen, Hermann C., Linsenmeier, Luise, Chakroun, Karima, Wegwitz, Florian, Piontek, Ulrike K., Tatzelt, Jörg, Bate, Clive, Magnus, Tim, Glatzel, Markus, Supattapone, Surachai

Journal:

Year:

2019

Language:

english

File:

PDF, 11.53 MB

english, 2019

27

[Topics in Current Chemistry] Prion Proteins Volume 305 || Neuroprotective and Neurotoxic Signaling by the Prion Protein

Year:

2012

Language:

english

File:

PDF, 1.01 MB

english, 2012

28

The Novel Membrane Protein TMEM59 Modulates Complex Glycosylation, Cell Surface Expression, and Secretion of the Amyloid Precursor Protein

Ullrich, Sylvia, Münch, Anna, Neumann, Stephanie, Kremmer, Elisabeth, Tatzelt, Jörg, Lichtenthaler, Stefan F.

Journal:

Journal of Biological Chemistry

Year:

2010

Language:

english

File:

PDF, 3.85 MB

english, 2010

29

The Cellular Prion Protein: A Player in Immunological Quiescence

Bakkebø, Maren K., Mouillet-Richard, Sophie, Espenes, Arild, Goldmann, Wilfred, Tatzelt, Jörg, Tranulis, Michael A.

Journal:

Frontiers in Immunology

Year:

2015

Language:

english

File:

PDF, 800 KB

english, 2015

30

Cationic Lipopolyamines Induce Degradation of PrPSc in Scrapie-Infected Mouse Neuroblastoma Cells

Winklhofer, K.F., Tatzelt, J.

Journal:

Biological Chemistry

Year:

2000

Language:

english

File:

PDF, 243 KB

english, 2000

31

Aberrant Folding of Pathogenic Parkin Mutants: AGGREGATION VERSUS DEGRADATION

Schlehe, J. S., Lutz, A. K., Pilsl, A., Lammermann, K., Grgur, K., Henn, I. H., Tatzelt, J., Winklhofer, K. F.

Journal:

Journal of Biological Chemistry

Year:

2008

Language:

english

File:

PDF, 433 KB

english, 2008

32

Impaired transport of intrinsically disordered proteins through the Sec61 and SecY translocon; implications for prion diseases

Jung, Sebastian, Tatzelt, Jörg

Journal:

Year:

2018

Language:

english

File:

PDF, 856 KB

english, 2018

33

Molecular basis of cerebral neurodegeneration in prion diseases

Jörg Tatzelt, Hermann M. Schätzl

Journal:

Year:

2007

Language:

english

File:

PDF, 532 KB

english, 2007

34

Parkinson's disease-associated genes and mitochondrial integrity

A. Kathrin Lutz, Anna Pilsl, Lena Bouman, Jörg Tatzelt, Konstanze F. Winklhofer

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

2010

Language:

english

File:

PDF, 54 KB

english, 2010

35

Pathogenic mutations inactivate parkin by distinct mechanisms

Iris H. Henn, Johanna M. Gostner, Peter Lackner, Jörg Tatzelt, Konstanze F. Winklhofer

Journal:

Journal of Neurochemistry

Year:

2005

Language:

english

File:

PDF, 466 KB

english, 2005

36

Determinants of the in Vivo Folding of the Prion Protein: A BIPARTITE FUNCTION OF HELIX 1 IN FOLDING AND AGGREGATION

Winklhofer, K. F., Heske, J., Heller, U., Reintjes, A., Muranyi, W., Moarefi, I., Tatzelt, J.

Journal:

Journal of Biological Chemistry

Year:

2003

Language:

english

File:

PDF, 932 KB

english, 2003

37

Cytoplasmic protein aggregates interfere with nucleo-cytoplasmic transport of protein and RNA

Woerner, A. C., Frottin, F., Hornburg, D., Feng, L. R., Meissner, F., Patra, M., Tatzelt, J., Mann, M., Winklhofer, K. F., Hartl, F. U., Hipp, M. S.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.19 MB

english, 2015

38

The Sec61/SecY complex is inherently deficient in translocating intrinsically disordered proteins

Gonsberg, Anika, Jung, Sebastian, Ulbrich, Sarah, Origi, Andrea, Ziska, Anke, Baier, Michael, Koch, Hans-Georg, Zimmermann, Richard, Winklhofer, Konstanze F., Tatzelt, Jörg

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 9.91 MB

english, 2017

39

Prion protein expression in Chinese hamster ovary cells using a glutamine synthetase selection and amplification system

Blochberger, T. C., Cooper, C., Peretz, D., Tatzelt, J., Griffith, O. H., Baldwin, M. A., Prusiner, S. B.

Journal:

Protein Engineering Design and Selection

Year:

1997

Language:

english

File:

PDF, 362 KB

english, 1997

40

[Topics in Current Chemistry] Prion Proteins Volume 305 || Atypical Prion Diseases in Humans and Animals

Year:

2012

Language:

english

File:

PDF, 385 KB

english, 2012

41

Mitochondrial Function in Human Neuroblastoma Cells Is Up-Regulated and Protected by NQO1, a Plasma Membrane Redox Enzyme

Kim, Jiyeong, Kim, Su-Kyung, Kim, Hwa-Kyung, Mattson, Mark P., Hyun, Dong-Hoon, Tatzelt, Jörg

Journal:

Year:

2013

Language:

english

File:

PDF, 1.16 MB

english, 2013

42

Scrapie in mice deficient in apolipoprotein E or glial fibrillary acidic protein

Tatzelt, J., Maeda, N., Pekny, M., Yang, S.-L., Betsholtz, C., Eliasson, C., Cayetano, J., Camerino, A. P., DeArmond, S. J., Prusiner, S. B.

Journal:

Year:

1996

File:

PDF, 985 KB

1996

43

SecY-mediated quality control prevents the translocation of non-gated porins

Jung, Sebastian, Bader, Verian, Natriashvili, Ana, Koch, Hans-Georg, Winklhofer, Konstanze F., Tatzelt, JÃ¶rg

Journal:

Scientific Reports

Year:

2020

File:

PDF, 4.69 MB

2020

44

[Topics in Current Chemistry] Prion Proteins Volume 305 || Genetics of Prion Disease

Year:

2011

Language:

english

File:

PDF, 239 KB

english, 2011

45

p53 Aggregates Penetrate Cells and Induce the Co-Aggregation of Intracellular p53

Forget, Karolyn J., Tremblay, Guillaume, Roucou, Xavier, Tatzelt, Jörg

Journal:

Year:

2013

Language:

english

File:

PDF, 1.17 MB

english, 2013

46

Parkin: A stress-protective E3 ubiquitin ligase maintaining mitochondrial integrity

Lutz, A. Kathrin, Pilsl, Anna, Beaudette, Patrick, Hadian, Kamyar, Augustin, Regina, Wurst, Wolfgang, Trümbach, Dietrich, Langer, Thomas, Krappmann, Daniel, Dittmar, Gunnar, Tatzelt, Jörg, Winklhofer,

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

2012

Language:

english

File:

PDF, 140 KB

english, 2012

47

Different effects of Sec61 , Sec62 and Sec63 depletion on transport of polypeptides into the endoplasmic reticulum of mammalian cells

Lang, S., Benedix, J., Fedeles, S. V., Schorr, S., Schirra, C., Schauble, N., Jalal, C., Greiner, M., Hassdenteufel, S., Tatzelt, J., Kreutzer, B., Edelmann, L., Krause, E., Rettig, J., Somlo, S., Zim

Journal:

Journal of Cell Science

Year:

2012

Language:

english

File:

PDF, 2.09 MB

english, 2012

48

Inhibition of Complex Glycosylation Increases the Formation of PrPsc

Konstanze F. Winklhofer, Ulrich Heller, Anja Reintjes, Jörg Tatzelt

Journal:

Year:

2003

Language:

english

File:

PDF, 1.57 MB

english, 2003

49

Prion protein-related proteins from zebrafish are complex glycosylated and contain a glycosylphosphatidylinositol anchor

Margit Miesbauer, Theresa Bamme, Constanze Riemer, Birgit Oidtmann, Konstanze F. Winklhofer, Michael Baier, Jörg Tatzelt

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 436 KB

english, 2006

50

Post-translational Import of the Prion Protein into the Endoplasmic Reticulum Interferes with Cell Viability: A CRITICAL ROLE FOR THE PUTATIVE TRANSMEMBRANE DOMAIN

Heller, U., Winklhofer, K. F., Heske, J., Reintjes, A., Tatzelt, J.

Journal:

Journal of Biological Chemistry

Year:

2003

Language:

english

File:

PDF, 464 KB

english, 2003

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